Phuong Thi Ngoc Cao

Phd Student (Group member from 2009 until 2014) + 32 (0) 9 33 13 825 VIB / Ghent University Bioinformatics & Systems Biology Technologiepark 927 B-9052 Gent BELGIUM

CV

• 2006-2009: Department of Molecular and Environmental Biotechnology, Faculty of Biology, University of Natural Sciences, Vietnam National University-Ho Chi Minh City, Vietnam.
• 2003-2009: Member of the Collaborative Bioinformatics Lab, Stuttgart - Hanoi - Ho Chi Minh City;
• 2004-2006: MSc., Microbiology, University of Natural Sciences, VNU-HCMC, Vietnam.
• 1999-2003: BSc., Biotechnology, University of Natural Sciences, VNU-HCMC, Vietnam.

Research

Spider mite Genome Annotation

Chelicerates (scorpions, horseshoe crabs, spiders, mites and ticks) are the second largest group of arthropods. The development of a chelicerate model system has been hampered by their complex ontogeny, long development time and large genomes. The two-spotted spider mite, Tetranychus urticae, is choosing as chelicerate genetic model because of many reasons:

1. the smallest genome of any arthropod,
2. extremely rapid development,
3. being maintained easily in the laboratory and
4. one of the major pests of agricultural crops.

The initial step to develop the genetic model requires integration of bioinformatics with genomics and genetics to establish the genetic bases in spider mite. Therefore, we are taking part in analyzing the spider mite genome. We use EnGene, a gene prediction platform for eukaryotes, for genome annotation of T. urticae.

Papers

(2) Thi Ngoc Cao, P., Greenhalgh, R., Dermauw, W., Rombauts, S., Bajda, S., Zhurov, V., Grbić, M., Van de Peer, Y., Van Leeuwen, T., Rouzé, P., M. Clark, R. (2016) Complex evolutionary dynamics of massively expanded chemosensory receptor families in an extreme generalist chelicerate herbivore. Genome Biol. Evol. 8(11):3323-3339.

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(1) Grbic, M., Van Leeuwen, T., Clark, T. G., Rombauts, S., Rouzé, P., Grbic, V., Osborne, E., Dermauw, W., Thi Ngoc Cao, P., Ortego, F., Hernandez-Crespo, P., Diaz, I., Martinez, N.J., Navajas, M., Sucena, E., Magalhaes, S., Nagy, L., Pace, N.R., Djuranovic, S., Smagghe, G., Iga, M., Christiaens, M., Veenstra, J., Ewer, J., Mancilla Villalobos, R., Hutter, J., Hudson, A., Velez, M., Yi, S., Zeng, Q., Pires-daSilva, A., Roch, F., Cazaux, M., Navarro, M., Zhurov, V., Acevedo, G., Bjelica, A., Fawcett, J., Bonnet, E., Martens, C., Baele, G., Wissler, L., Sanchez-Rodriguez, A., Tirry, L., Blais, C., Demeestere, K., Henz, SR., Gregory, R., Mathieu, J., Verdon, L., Farinelli, L., Schmutz, J., Lindquist, E., Feyereisen, R., Van de Peer, Y. (2011) The genome of Tetranychus urticae reveals herbivorous pest adaptations. Nature 479,487-492.

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